CVG Journal Club History

September 29, 2022 in T9006C VRT

• Discussion Topics: Ethical Issues in Genomics and DEI in Science: LGBTQ+ in STEM
• Alexx Shumway (Sethupathy Lab)
  Gonsalves GS, Mayer K, Beyrer C. Déjà vu All Over Again? Emergent Monkeypox, Delayed Responses, and Stigmatized Populations. Journal of Urban Health. 2022 Aug;99(4):603-6. Article
• Renna Costa (Crickard Lab)
  Tarazi S, Aguilera-Castrejon A, Joubran C, Ghanem N, Ashouokhi S, Roncato F, Wildschutz E, Haddad M, Oldak B, Gomez-Cesar E, Livnat N. Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs. Cell. 2022 Sep 1;185(18):3290-306. Article

October 27, 2022 in 221 Weill

• Brian Aguilera (Kurpios Lab)
  DEI in Science: Lack of Diversity in Biobanks
  Fatumo S, Chikowore T, Choudhury A, Ayub M, Martin AR, Kuchenbaecker K. A roadmap to increase diversity in genomic studies. Nature Medicine. 2022 Feb;28(2):243-50. Article
• Heesoo Jeong (Vacanti Lab)
  Computational Modeling Techniques for Genomics
  Katzir R, Polat IH, Harel M, Katz S, Foguet C, Selivanov VA, Sabatier P, Cascante M, Geiger T, Ruppin E. The landscape of tiered regulation of breast cancer cell metabolism. Scientific reports. 2019 Nov 28;9(1):1-2. Article

December 1, 2022 in T9006C VRT

• Sagar R. Shah (Lis and Yu Labs)
  DEI in Science: Scientific Communication & Social Media
  Habibi, Sarah A., and Lidya Salim. "Static vs. dynamic methods of delivery for science communication: A critical analysis of user engagement with science on social media." PLoS One 16.3 (2021): e0248507. Article
• Chloe Cheng (Barrow Lab)
  Li VL, He Y, Contrepois K, Liu H, Kim JT, Wiggenhorn AL, Tanzo JT, Tung AS, Lyu X, Zushin PJ, Jansen RS. An exercise-inducible metabolite that suppresses feeding and obesity. Nature. 2022 Jun;606(7915):785-90. Article

May 5, 2022
  DEI in Science: AAPI Heritage Month

• Elena Panizza (Cerione lab)
  Pensky J, Richardson C, Serrano A, Gorski G, Price AN, Zimmer M. Disrupt and demystify the unwritten rules of graduate school. Nature Geoscience. 2021 Aug;14(8):538-9. Article
• Blake Mitchell (Aydemir lab)
  Laudisi F, Stolfi C, Bevivino G, Maresca C, Franzè E, Troncone E, Lolli E, Marafini I, Pietrucci D, Teofani A, Di Grazia A, Di Fusco D, Colantoni A, Ortenzi A, Desideri A, Monteleone I, Monteleone G. GATA6 Deficiency Leads to Epithelial Barrier Dysfunction and Enhances Susceptibility to Gut Inflammation. J Crohns Colitis. 2022 Feb 23;16(2):301-311. doi: 10.1093/ecco-jcc/jjab145. PMID: 34374415. pdf

March 31, 2022
  DEI in Science: Women's History Month

• Anusha Shankar (Lovette and Vitousek labs)
  Responses to 10 Common Criticisms of Anti-Racism Action in STEM
• Matt Edwards (Koren lab)
  Nakatani T, Lin J, Ji F, Ettinger A, Pontabry J, Tokoro M, Altamirano-Pacheco L, Fiorentino J, Mahammadov E, Hatano Y, Van Rechem C. DNA replication fork speed underlies cell fate changes and promotes reprogramming. Nature Genetics. 2022 Mar 7:1-0. Article

January 27, 2022
  DEI in Science: Mentorship of Minorities in STEM

• Madhav Mantri (De Vlaminck lab)
  The Role of Mentoring in Promoting Diversity, Equity, and Inclusion in STEM Education and Research Andrea G. Marshall, Zer Vue, Caroline B. Palavicino-Maggio, Elsie C. Spencer, Heather K. Beasley, Edgar Garza-Lopez, Zachary Conley, Kit Neikirk, Sandra A. Murray, Denise Martinez, Jamaine Davis, Lillian Brady, Haysetta D. Shuler, Derrick Morton, Antentor Hinton Jr. doi: https://doi.org/10.1101/2021.12.08.471502 Preprint
• Carolline Ascencao (Smolka lab)
  Phosphoproteomics of ATR signaling in mouse testes. Sims JR, Faca VM, Periera C, Ascencao C, Comstock W, Bada J, Arroyo-Martinez GA, Freire R, Cohen PE, Weiss RS, Smolka MB. eLife. In Press.

December 2, 2021
  Genomics & the Gut Microbiome
  DEI in Science: Native American Heritage Month

• Rosanna Ma (Sethupathy lab)
  Burns AR, Miller E, Agarwal M, Rolig AS, Milligan-Myhre K, Seredick S, Guillemin K, Bohannan BJ. Interhost dispersal alters microbiome assembly and can overwhelm host innate immunity in an experimental zebrafish model. Proceedings of the National Academy of Sciences. 2017 Oct 17;114(42):11181-6. pdf
• Min-Ting Lee (E. Johnson lab)
  Javdan B, Lopez JG, Chankhamjon P, Lee YC, Hull R, Wu Q, Wang X, Chatterjee S, Donia MS. Personalized mapping of drug metabolism by the human gut microbiome. Cell. 2020 Jun 25;181(7):1661-79. Article
• Kaydine Edwards (Barrow lab)
  Bjursell MK, Martens EC, Gordon JI. Functional genomic and metabolic studies of the adaptations of a prominent adult human gut symbiont, Bacteroides thetaiotaomicron, to the suckling period. Journal of biological chemistry. 2006 Nov 24;281(47):36269-79. Article

October 28, 2021
  Cancer Genomics (Breast Cancer Awareness Month)
  DEI in Science: Disparities in Health Care

• Austin Hovland (Simoes-Costa lab)
  Vrdoljak E, Gligorov J, Wierinck L, Conte P, De Grève J, Meunier F, Palmieri C, Travado L, Walker A, Wiseman T, Wuerstlein R. Addressing disparities and challenges in underserved patient populations with metastatic breast cancer in Europe. The Breast. 2020 Dec 13. Article
• Madhav Mantri (De Vlaminck lab)
  Oren Y, Tsabar M, Cuoco MS, Amir-Zilberstein L, Cabanos HF, Hütter JC, Hu B, Thakore PI, Tabaka M, Fulco CP, Colgan W. Cycling cancer persister cells arise from lineages with distinct programs. Nature. 2021 Aug;596(7873):576-82. Article
• Adam He (Danko lab)
  Akdemir KC, Le VT, Kim JM, Killcoyne S, King DA, Lin YP, Tian Y, Inoue A, Amin SB, Robinson FS, Nimmakayalu M. Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure. Nature Genetics. 2020 Nov;52(11):1178-88. Article

September 30, 2021
  Genomics of Companion Animals
  DEI in Science: Hispanic / Latinx Heritage Month

• Hector Loyola Irizarry (Brito lab)
  Danila MI, Allison JJ, Goins KV, Chiriboga G, Fischer M, Puliafico M, Mudano AS, Rahn EJ, Merchant J, Lawrence CE, Dunkel L. Development of a multi-component intervention to promote participation of Black and Latinx individuals in biomedical research. Journal of Clinical and Translational Science. 2021;5(1). Article
• Tatiane Kanno (Simoes-Costa lab)
  Bannasch DL, Kaelin CB, Letko A, Loechel R, Hug P, Jagannathan V, Henkel J, Roosje P, Hytönen MK, Lohi H, Arumilli M. Dog colour patterns explained by modular promoters of ancient canid origin. Nature ecology & evolution. 2021 Aug 12:1-9. Article
• Sylvia Chang (Feschotte lab)
  Kwon Y, Vranken N, Hoge C, Lichak MR, Francis KX, Camacho-Garcia J, Bista I, Wood J, McCarthy S, Chow W, Tan HH. Genomic consequences of domestication of the Siamese fighting fish. bioRxiv. 2021 Jan 1. Article

May 27, 2021

• Viviana Maymi (Rudd Lab)
  Temba GS, Kullaya V, Pecht T, Mmbaga BT, Aschenbrenner AC, Ulas T, Kibiki G, Lyamuya F, Boahen CK, Kumar V, Joosten LA. Urban living in healthy Tanzanians is associated with an inflammatory status driven by dietary and metabolic changes. Nature Immunology. 2021 Mar;22(3):287-300. Article
• Josh Jones (Brito Lab)
  Cheng S, Li Z, Gao R, Xing B, Gao Y, Yang Y, Qin S, Zhang L, Ouyang H, Du P, Jiang L. A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells. Cell. 2021 Feb 4;184(3):792-809. Article

April 29, 2021

• Alexandra Chivu (Danko Lab) and Ethan Sanford (Smolka Lab)
  Mahdessian D, Cesnik AJ, Gnann C, Danielsson F, Stenström L, Arif M, Zhang C, Le T, Johansson F, Shutten R, Bäckström A. Spatiotemporal dissection of the cell cycle with single-cell proteogenomics. Nature. 2021 Feb;590(7847):649-54. Article
• Mauricio Paramo (H. Yu Lab)
  Lee JD, Paulo JA, Posey RR, Mugoni V, Kong NR, Cheloni G, Lee YR, Slack FJ, Tenen DG, Clohessy JG, Gygi SP. Dual DNA and protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia. Nature Methods. 2021 Mar;18(3):293-302. Article

March 25, 2021 4:00 - 4:30 pm

• Divya Ganapathi Sankaran (Grimson Lab)
  Coyle SM, Flaum EM, Li H, Krishnamurthy D, Prakash M. Coupled active systems encode an emergent hunting behavior in the unicellular predator Lacrymaria olor. Current Biology. 2019 Nov 18;29(22):3838-50. Article
• Watch a video of hunting behavior! video

February 25, 2021

• Lauren Walter (Cosgrove Lab)
  Eyler CE, Matsunaga H, Hovestadt V, Vantine SJ, van Galen P, Bernstein BE. Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance. Genome biology. 2020 Dec;21(1):1-21. Article
• Adriana Alexander (Cohen & Danko Labs)
  Maxwell KG, Augsornworawat P, Velazco-Cruz L, Kim MH, Asada R, Hogrebe NJ, Morikawa S, Urano F, Millman JR. Gene-edited human stem cell–derived β cells from a patient with monogenic diabetes reverse preexisting diabetes in mice. Science translational medicine. 2020 Apr 22;12(540). Article
• Sangeeta Ghuwalewala (Tumbar Lab)
  Ji AL, Rubin AJ, Thrane K, Jiang S, Reynolds DL, Meyers RM, Guo MG, George BM, Mollbrink A, Bergenstråhle J, Larsson L. Multimodal analysis of composition and spatial architecture in human squamous cell carcinoma. Cell. 2020 Jul 23;182(2):497-514. Article

January 28, 2021

• Austin Hovland (Simoes-Costa lab)
  da Silveira WA, Fazelinia H, Rosenthal SB, Laiakis EC, Kim MS, Meydan C, Kidane Y, Rathi KS, Smith SM, Stear B, Ying Y. Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact. Cell. 2020 Nov 25;183(5):1185-201. Article
• Kieran Koch-Laskowski (Sethupathy Lab)
  Malkani S, Chin CR, Cekanaviciute E, Mortreux M, Okinula H, Tarbier M, Schreurs AS, Shirazi-Fard Y, Tahimic CG, Rodriguez DN, Sexton BS. Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development. Cell Reports. 2020 Dec 8;33(10):108448. Article

December 3, 2020

• Albert Vill (Brito Lab)
  Ignacio-Espinoza JC, Laperriere S, Yeh YC, Weissman J, Hou S, Long A, Fuhrman JA. Ribosome-linked mRNA-rRNA chimeras reveal active novel virus-host associations. bioRxiv. 2020 Oct 30. Article

October 29, 2020

• R. Nicolas Lou (Therkildsen lab)
  Margaryan A, Lawson DJ, Sikora M, Racimo F, Rasmussen S, Moltke I, Cassidy LM, Jørsboe E, Ingason A, Pedersen MW, Korneliussen T. Population genomics of the Viking world. Nature. 2020 Sep;585(7825):390-6. Article
• Seoyeon Lee(Soloway lab)
  Oguri Y, Shinoda K, Kim H, Alba DL, Bolus WR, Wang Q, Brown Z, Pradhan RN, Tajima K, Yoneshiro T, Ikeda K. CD81 controls beige fat progenitor cell growth and energy balance via FAK signaling. Cell. 2020 Aug 6;182(3):563-77. Article
• Luye An (White lab)
  Shwartz Y, Gonzalez-Celeiro M, Chen CL, Pasolli HA, Sheu SH, Fan SM, Shamsi F, Assaad S, Lin ET, Zhang B, Tsai PC. Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells. Cell. 2020 Aug 6;182(3):578-93. Article

September 24, 2020

• Bhargav Sanketi (Kurpios lab)
  Wang W, Hu CK, Zeng A, Alegre D, Hu D, Gotting K, Granillo AO, Wang Y, Robb S, Schnittker R, Zhang S. Changes in regeneration-responsive enhancers shape regenerative capacities in vertebrates. Science. 2020 Sep 4;369(6508). Article
• Ky'ara Carr (Cohen lab)
  He W, Rao HP, Tang S, Bhagwat N, Kulkarni DS, Ma Y, Chang MA, Hall C, Bragg JW, Manasca HS, Baker C. Regulated proteolysis of MutSγ controls meiotic crossing over. Molecular cell. 2020 Apr 2. Article

May 28, 2020 Blitz Format

• Nicolas Lou (Therkildsen lab)
  Campbell-Staton SC, Winchell KM, Rochette NC, Fredette J, Maayan I, Schweizer RM, Catchen J. Parallel selection on thermal physiology facilitates repeated adaptation of city lizards to urban heat islands. Nature Ecology & Evolution. 2020 Apr;4(4):652-8. Article
• Seoyeon Lee (Soloway lab)
  Hu B, Jin C, Zeng X, Resch JM, Jedrychowski MP, Yang Z, Desai BN, Banks AS, Lowell BB, Mathis D, Spiegelman BM. γδ T cells and adipocyte IL-17RC control fat innervation and thermogenesis. Nature. 2020 Feb;578(7796):610-4. Article
• Luye An (White lab)
  Gur-Cohen S, Yang H, Baksh SC, Miao Y, Levorse J, Kataru RP, Liu X, de la Cruz-Racelis J, Mehrara BJ, Fuchs E. Stem cell–driven lymphatic remodeling coordinates tissue regeneration. Science. 2019 Dec 6;366(6470):1218-25. Article
• Jackie Copeland (Simoes-Costa lab)
  Basu S, Mackowiak SD, Niskanen H, Knezevic D, Asimi V, Grosswendt S, Geertsema H, Ali S, Jerković I, Ewers H, Mundlos S. Unblending of Transcriptional Condensates in Human Repeat Expansion Disease. Cell. 2020 May 7. Article

April 30, 2020

• Alexandra Chivu (Danko Lab)
• Jadhav, Unmesh, et al. "Replicational Dilution of H3K27me3 in Mammalian Cells and the Role of Poised Promoters." Molecular Cell (2020). Article

February 27, 2020

• Marquita Winters (Schimenti Lab)
• Morova, T., McNeill, D.R., Lallous, N. et al. Androgen receptor-binding sites are highly mutated in prostate cancer. Nat Commun 11, 832 (2020). Article

January 30, 2020 Blitz Format

• Albert Vill (Brito lab)
  de Boer CG, Vaishnav ED, Sadeh R, Abeyta EL, Friedman N, Regev A. Deciphering eukaryotic gene-regulatory logic with 100 million random promoters. Nature Biotechnology. 2020 Jan;38(1):56-65. Article
• Hector Loyola Irizarry (Brito lab)
  Weissman JL, Johnson PL. Network-Based Prediction of Novel CRISPR-Associated Genes in Metagenomes. mSystems. 2020 Feb 25;5(1). Article
• Jackie Copeland (Simoes-Costa lab)
  Zhang B, Ma S, Rachmin I, He M, Baral P, Choi S, Gonçalves WA, Shwartz Y, Fast EM, Su Y, Zon LI. Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells. Nature. 2020 Jan;577(7792):676-81. Article
• Luye An (White lab)
  Zhang, B., Ma, S., Rachmin, I., et al. "Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells." Nature (2020) Article

October 3, 2019

• Austin Hovland (Simoes-Costa Lab)
• Benabdallah, Nezha S., et al. "Decreased enhancer-promoter proximity accompanying enhancer activation." Molecular cell (2019). PDF

October 24, 2019

• Gaetano Scuderi (Butcher Lab)
• Cui, Yueli, et al. "Single-cell transcriptome analysis maps the developmental track of the human heart." Cell reports 26.7 (2019): 1934-1950. Article

December 5, 2019 Blitz Format

• Adam Franciso (Sethupathy lab)
  Zhang, Di, et al. "Metabolic regulation of gene expression by histone lactylation." Nature 574.7779 (2019): 575-580. Article
• Austin Hovland (Simoes-Costa lab)
  Siebert, Stefan, et al. "Stem cell differentiation trajectories in Hydra resolved at single-cell resolution." Science 365.6451 (2019): eaav9314. Article
• Adriana Alexander (Danko and Cohen labs)
  Luense, Lacey J., et al. "Gcn5-Mediated Histone Acetylation Governs Nucleosome Dynamics in Spermiogenesis." Developmental Cell (2019). Article
• Albert Vill (Brito lab)
  Anzalone, Andrew V., et al. "Search-and-replace genome editing without double-strand breaks or donor DNA." Nature (2019): 1-1. Article

May 30, 2019

• Tommy Carter
• Pontis, Julien, et al. "Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs." Cell stem cell (2019). Article

Apr 25, 2019

• Marlena Holter
• Furuyama, Kenichiro, et al. "Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells." Nature 567.7746 (2019): 43. Article

Mar 28, 2019

• Alexa Bracci
• Kronenberg ZN et al. High-resolution comparative analysis of great ape genomes. Science 360: eaar6343 (2018) Article

Feb 28, 2019

• Amanda Touey
• Conine, Colin C., et al. "Small RNAs gained during epididymal transit of sperm are essential for embryonic development in mice." Developmental cell 46.4 (2018): 470-480. Article

Jan 31, 2019

• Debbie Bhattacharya
• Sima, Jiao, et al. "Identifying cis Elements for Spatiotemporal Control of Mammalian DNA Replication." Cell (2018). Article

Dec 6, 2018

• Siwei Chen
• Werling, Donna M., et al. "An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder." Nat Genet 50 (2018): 727-736. PDF

Oct 25, 2018

• Jessica West
• Kleaveland, B., et al. (2018). "A network of noncoding regulatory RNAs acts in the mammalian brain." Cell 174 (2): 350-62 Article

Sep 27, 2018

• Maria Akopyan
• "Red fox genome assembly identifies genomic regions associated with tame and aggressive behaviours." Kukekova, AV et al., Nature Evolution & Ecology (2018) doi: 10.1038/s41559-018-0611-6 Article

Apr 26, 2018

• Megan Rothstein
• Priessl, S. et al. (2018). "Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation." Nature Neuroscience 3: 432-39. Article

Mar 29, 2018

• Katla Kristjánsdóttir
• Alasoo, K et al. (2018). "Shared genetic effects on chromatin and gene expression indicate a role for enhancer priming in immune response". Nature Genetics Article

Feb 22, 2018

• Jordana Bloom
• Thion, MS et al. (2017) "Microbiome influences prenatal and adult microglia in a sex-specific manner". Cell. 172(3): 500-516 Article

Jan 25, 2018

• Emily Funk
• Campbell-Staton, Shane C., et al. "Winter storms drive rapid phenotypic, regulatory, and genomic shifts in the green anole lizard." Science 357.6350 (2017): 495-498. Article

Dec 7, 2017

• Ian Rose
• Simeonov et al. (2017). "Discovery of stimulation-responsive immune enhancers with CRISPR activation". Nature. Article

Oct 26, 2017

• Darshil Patel
• Vaz, M. et al. (2017). "Chronic cigarette smoke-induced epigenomic changes precede sensitization of bronchial epithelial cells to single-step transformation by KRAS mutations". Cancer Cell. 32(3): 360-376. Article

Sep 28, 2017

• Lauren Choate
• Rubin, Adam J., et al. "Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation." Nature genetics (2017). PDF

May 25, 2017

• Sangjo Kang (Tumbar Lab)
• Petruk, S et al. (2017). “Delayed accumulation of H3K27me3 on nascent DNA is essential for recruitment of transcription factors at early stages of stem cell differentiation”. Molecular Cell 66(2): 247-2 Article

Apr 27, 2017

• Roman Spektor (Soloway Lab)
• Minoux, M. et al.​ (2017). "Gene bivalency at Polycomb domains regulates cranial neural crest positional identity".Science 355(6332​). doi: 10.1126/science.aal2913​ Article

Mar 30, 2017

• Brooke Marks
• Xu et al. (2017). "Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells" Nature Genetics 49:377-386. doi:10.1038/ng.3769 Article

Feb 23, 2017

• Jiayi Xu (Cassano Lab)
• Liu et al. (2017) "CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells" Science 355(39). DOI: 10.1126/science.aah7111 Article

Jan 26, 2017

• Nate Tippens (Lis/Yu Labs)
• Rafiee, Mahmoud-Reza, et al. "Expanding the circuitry of pluripotency by selective isolation of chromatin-associated proteins." Molecular Cell 64.3 (2016): 624-635. Article

Nov 17, 2016

• Sunny Moon (White Lab)
• Guernet, Alexis, et al. "CRISPR-Barcoding for Intratumor Genetic Heterogeneity Modeling and Functional Analysis of Oncogenic Driver Mutations." Molecular cell 63.3 (2016): 526-538. Article

Oct 27, 2016

• Jennie Sims (Smolka Lab)
• Canela, A. et al. (2016) "DNA breaks and end resection measured genome-wide by End Sequencing" Molec. Cell 63: 898-911

Sep 29, 2016

• Joel Tripp
• “Microglia development follows a stepwise program to regulate brain homeostasis” Matcovitch-Natan, O et al., Science (2016) doi: 10.1126/science.aad8670 Article

May 26, 2016

• Peter Schweitzer (Genomics Core Facility)
• Understanding factors involved in Illumina sequencing: the unvarnished truth of Illumina sequencing technologies and platforms.

Apr 28, 2016

• Ezen Choo
• “Ancient transposable elements transformed the uterine regulatory landscape and transcriptome during the evolution of mammalian pregnancy”Lynch, VJ et al., Cell Reports 10(4): 551-561 (2015) Article
  "Transposable elements and their KRAP-ZFP controllers regulate gene expression in adult tissues." Ecco, G et al. Developmental Cell 36(6): 611-623 (2016) Article

Mar 24, 2016

• Anne McGavigan
• “Genome-wide footprinting: ready for prime time?” Sung, MH et al., Nature 13: 222-228 (2016) Article
  “DNAse footprint signatures are dictated by factor dynamics and DNA sequence” Sung, MH et al., Nature 56(2): 275-285 (2014) Article

Feb 25, 2016

• Joel Brown
• “Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder.” Chen, Q et al., Science 351(6271):397-400 (2016) Article

Jan 28, 2016

• Presenters: John Lis and Jay Mahat
• Presentations: “Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers.” Core, LJ et al., Nat Genetics 46(12):1311-20 (2014) Article
  “Precise maps of RNA polymerase reveal how promoters direct initiation and pausing.” Kwak, H et al., Science 339(6122):950-3 (2013) Article

Nov 19, 2015

• Nithya Kartha
• Konermann, Silvana, et al. "Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex." Nature 517:583-88 (2014). Article
  Hilton, et al. "Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers." Nat Biotechnology 33:510-517 (2015) Article

Oct 29, 2015

• David Taylor
• Lupiáñez DG et al. "Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions." Cell. 2015 May 21;161(5):1012-25. Article

Sep 17, 2015

• Adam Bisogni
• Buenrostro, Jason D., et al. "Single-cell chromatin accessibility reveals principles of regulatory variation." Nature 523.7561 (2015): 486-490 Article