PubMed Vertebrate Genomics Feed
This is an RSS feed from PubMed (https://pubmed.ncbi.nlm.nih.gov/) of the 20 most recent papers published by CVG Members.
- by Chia-Hsin HsuTargeted kinase inhibitors induce marked tumor regressions but are limited by the emergence of drug-tolerant residual disease and resistance. Although tumor-intrinsic and adaptive immune mechanisms have been extensively studied, a better understanding of the contribution of innate immunity to targeted therapy durability is needed to devise […]
- by Cailin E WinokurWhile the gross dental anatomy of the Virginia opossum (Didelphis virginiana) has been described, the radiographic appearance of the dentition and the prevalence of dental and oral pathology have not been comprehensively evaluated. The objective of this study was to characterize the intraoral radiographic dental anatomy […]
- by Paul R MunnFunctional element annotations are critical tools used to provide insight into the molecular processes governing cell development, differentiation, and disease. Run-on and sequencing assays measure the production of nascent RNAs and can provide an effective data source for discovering functional elements. However, the accurate inference of […]
- by Catherine RenaudinThe objectives of this clinical case report were to highlight the value of late transrectal ultrasound examination for assessing fetal presentation, position and posture and to describe the management of a case of malposture associated with musculoskeletal and cerebellar abnormalities, including its in utero ultrasound diagnosis […]
- by Huihui LiuRNA pesticides have garnered considerable attention in pest management due to their exceptional selectivity, environmental safety, and flexible design. They interfere with essential physiological processes in pests by silencing key genes, thereby achieving effective pest control. Moreover, RNA pesticides can target genes related to detoxification enzymes […]
- by Omar A Gonzales-VieraCanine parvovirus 2a (CPV-2a) causes severe enteritis and diarrhea in unvaccinated domestic puppies and wild mesocarnivores, such as raccoons (Procyon lotor). A retrospective and prospective study was conducted to characterize CPV-induced encephalomyelitis in mountain lions (Puma concolor) from California. Four free-ranging juvenile mountain lions were euthanized […]
- by Deepthi MahishiTaste perception is a major determinant of food intake and is dynamically modulated by hunger and satiety signals across species. While the peripheral and cortical representations of taste sensory stimuli are well characterized, far less is known about how metabolic state shapes taste processing in subcortical […]
- by Peiwei ChenIn Metazoa, transposon expression is suppressed by the piRNA pathway, and disruption of this pathway leads to rampant transposon expression. However, it remains unclear whether increased transposon expression results in actual transposition, and if so, which and how frequently transposons mobilize upon piRNA loss. Here, we […]
- by Brandon T JamesReactive aldehydes are potent electrophiles that damage DNA and can ultimately promote cancer. While many aldehydes are ubiquitous in the environment, mammalian metabolism also generates high levels of endogenous aldehydes sufficient to threaten genome integrity. To protect against these aldehyde genotoxins, mammalian cells rely on diverse […]
- by Patryk ZiobroPhysical activity offers myriad benefits to health and well-being, in humans and other animals as well. In rodents, voluntary wheel running can attenuate the effects of both physical and social stressors on rodent social behavior. Whether wheel running affects rodent social behaviors per se remains less […]
- by Cristian RiveraMuch like with statistical learning, there is a tendency in the cognitive and language science literature to treat chunking as a unitary, domain-general ability that operates fairly similarly across domains of cognition. An alternative position suggests chunking in language and cognition involves multiple mechanisms tuned to […]
- by Elisa PiperniResistant starch (RS) can confer benefits for the gut microbiome and host cardiometabolic health. However, different types of resistant starch can differentially affect gut microbiome composition and functional capacity, especially given interindividual variability in responses, thus limiting the application of resistant starch in dietary strategies. We […]
- by Mayzie MillerCONCLUSIONS: The angle of the LUC population on the ADVIA MPX cytogram cannot be used as a rapid test to differentiate AML from LL.
- by Patryk ZiobroAnimals produce different vocalization types, which differ in their acoustic features and are produced in different behavioral contexts. How vocalization-related brain circuits are organized to enable the production of different vocalization types remains poorly understood. The nucleus retroambiguus is a hindbrain premotor region that regulates the […]
- by Nathaniel P HernandezChronic primary pain conditions (CPPCs), such as fibromyalgia and vestibulodynia, affect over 100 million Americans, predominantly women, and pose a substantial healthcare challenge. CPPCs arise from genetic and environmental factors that enhance catecholamine tone, potentially through miRNA dysregulation following catecholamine activation of beta-adrenergic receptors. Here, we […]
- by Eric MaiCONCLUSIONS: Our study demonstrates improved clinical outcomes for patients with shorter preoperative symptom duration undergoing endoscopic lumbar discectomy, suggesting that delayed surgical intervention may result in poorer outcomes and greater postoperative disability. These findings may help inform the approach to counseling patients on postoperative expectations and […]
- by Zhou ZhouEnhancers are abundant and critical gene-distal cis-regulatory elements with distinct architectural features; however, a mechanistic understanding of their interactions within endogenous chromatin contexts remains challenging. Here, we developed a recombinase-mediated genome-rewriting platform to explore how a long-range human enhancer, eNMU, confers a remarkable 10,000-fold activation of […]
- by Zihao GaoRNA viruses represent an integral component of human-associated environments and human health. However, the ecology of environmental RNA viruses remains largely unexplored. Here, we analyzed 2922 metatranscriptomic samples collected from urban and surrounding environments-including human-dense settings (e.g., transit hubs, hospitals, banks), alongside peri-urban settings – across […]
- by Nuno Tiago TavaresTesticular cancer is the most common cancer in young adult men, and its incidence is increasing globally, with testicular germ cell tumors (TGCT) being the most frequent subtype. These tumors show remarkable sensitivity to cisplatin, but there is a small subset of patients that develop resistance […]
- by Tram N NguyenWhole-genome sequencing is proving to be highly informative about the past demography of free-living populations, and in the context of endangered species, it can provide a quantification of the genetic risk posed by reduced genetic diversity and inbreeding. Prior to 1920, the Florida scrub-jay (Aphelocoma coerulescens) […]