This is an RSS feed from PubMed (https://pubmed.ncbi.nlm.nih.gov/) of the 20 most recent papers published by CVG Members.

• An Open-Source Automated Pipeline for Quantitative Morphological Analysis of 3D-Bioprinted Cancer Cell Spheroids
  February 20, 2026 by Pius N Amartey
  Three-dimensional (3D) culture systems that recapitulate the tumor microenvironment are essential for studying cancer cell behavior, drug response, and cell-matrix interactions. Here, we present a detailed protocol for generating 3D spheroid cultures from murine breast cancer cells using methacrylated gelatin (GelMA)-based bioink and a CELLINK BioX […]
• Transcriptomic and chromatin accessibility profiling unveils new regulators of heat hormesis in Caenorhabditis elegans
  February 20, 2026 by Hsin-Yun Chang
  Heat hormesis describes the beneficial adaptations resulting from transient exposure to mild heat stress, which enhances stress resilience and promotes healthy aging. While heat hormesis is widely observed, much remains to be learned about its molecular basis. This study bridges a critical knowledge gap through a […]
• Impact of Preoperative PROMIS PF on Outcomes Following Cervical Disc Replacement
  February 19, 2026 by Cole T Kwas
  CONCLUSION: Patients with higher preoperative disability, as determined by PROMIS PF, experience similar postoperative pain scores, narcotics consumption, time to discontinue narcotics, and return to activities as compared with patients with lower preoperative disability undergoing CDR as well as greater absolute improvements and MCID achievement rates […]
• Late-season off-flavor impacts on consumer acceptance and perceived product value of maple syrup
  February 18, 2026 by Alina N Stelick
  Maple Syrup is an important agroforestry product in New York State (U.S. Department of Agriculture (USDA), National Agricultural Statistics Service, 2017), produced from the sap of maple trees in late winter-early spring. Climate change has compressed the sap harvesting season due to increased average temperatures and […]
• Engineering surgery-free prosthetic heart valve growth
  February 18, 2026 by Jonathan T Butcher
  Children with congenital heart valve disease require repeat surgical procedures to resize grafts. A new option is a valved stent that grows spontaneously.
• Network-based genetic monitoring of landscape fragmentation
  February 18, 2026 by Ohad Peled
  Habitat fragmentation is one of the most immediate and substantial threats to biodiversity, generating isolated populations with reduced genetic diversity. Genetic monitoring has become essential for detecting fragmentation and tracking its progress. However, the coherent interpretation of genetic monitoring data and understanding the genetic consequences of […]
• Overcoming CXCR4-Mediated T-Cell Exclusion Potentiates Antitumor Cytotoxicity in Fibrolamellar Carcinoma
  February 17, 2026 by Jason A Carter
  CONCLUSIONS: Our findings demonstrate that immune resistance in FLC is mediated by both local T-cell exclusion and exhaustion, with combination CXCR4 and PD-1 blockade acting cooperatively to overcome these independent mechanisms. These results highlight the versatility of the human TSC system to aid in the study […]
• Longitudinal Live Imaging-Derived 4D Hemodynamics and Dynamic Tissue Mechanics Across Outflow Tract Morphogenesis
  February 17, 2026 by Gening Dong
  CONCLUSION: We identified hemodynamic force and tissue mechanics as drivers of local tissue development and important stimuli for OFT remodeling and septation, advancing insights in how mechanical forces contribute to OFT development.
• PDGFRβ signaling restrains myocyte function to limit the regenerative capacity of skeletal muscle
  February 16, 2026 by Siwen Xue
  Muscle cell fusion is critical for the formation and maintenance of multinucleated myotubes during skeletal muscle development and regeneration. However, the molecular mechanisms directing cell-cell fusion are not fully understood. Here, we identified platelet-derived growth factor receptor β (PDGFRβ) signaling as a key modulator of myocyte […]
• Single-cell transcriptomics reveals targeted modulation of inflammatory repertoire by SOCE blockers
  February 14, 2026 by Andreas Stephanou
  Store-operated calcium entry (SOCE) plays a critical role in regulating intracellular calcium signaling and is essential for immune cell functions. SOCE blockade with the pyrazole derivative BTP2 has been explored as an anti-inflammatory strategy in preclinical models, and Zegocractin (CM4620) is under clinical investigation as a […]
• Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease
  February 12, 2026 by Guangyi Xu
  Epidemiological studies suggest a link between type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), possibly due to gut microbiota dysbiosis, although the exact mechanisms are unclear. This narrative review uniquely addresses how gut microbiota-derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in […]
• Molecular insights into diverse heat hormesis regimens in Caenorhabditis elegans
  February 12, 2026 by Hsin-Yun Chang
  Heat hormesis describes a biphasic, dose-dependent response in which low levels of heat stress induce beneficial effects, such as enhanced lifespan and stress resilience. This phenomenon is commonly studied in Caenorhabditis elegans using regimens that involve mild heat stress priming, followed by a recovery period and […]
• Smart DNA Hydrogel-Responsive Encoding Enables Portable Nucleic Acid Detection
  February 12, 2026 by Jie Luo
  DNA hydrogels are promising materials for biosensing, but translating their molecular recognition capabilities into portable diagnostics is hindered by slow target diffusion, signal constraints, and bulk architecture. Here, we present a smart DNA hydrogel-responsive sensing platform termed Q-RAPID (Quick Response Analysis for Pathogen Identification Device) for […]
• Keratin 5 marks cancer-propagating cells sustained by an osteopontin-producing niche in high-grade serous ovarian carcinoma
  February 9, 2026 by Mallikarjun Bidarimath
  High-grade serous carcinoma (HGSC) is the most common and aggressive form of ovarian cancer. Advanced HGSCs exhibit pronounced cellular heterogeneity, including a subset of cancer-propagating cells (CPCs, also known as cancer stem cells) that are highly tumorigenic and display stem cell-associated properties such as self-renewal and […]
• Comparing tree swallow dispersal strategies in a continuous mainland environment
  February 6, 2026 by Kelly K Hallinger
  Dispersal is one of the most important aspects of animal behavior and can have far-reaching consequences for organismal ecology and evolution. Despite recent theoretical advances in understanding why individuals within the same population vary in dispersal behavior, relatively few studies have empirically evaluated the long-term causes […]
• Cooperative and Opposing Functions of ANP32E and VPS72 Govern Gene Promoter Chromatin Status
  February 6, 2026 by Patrick Murphy
  The histone variant H2A.Z resides within active gene promoters, but how it influences chromatin state and nucleosome stability remains poorly understood. Here, we probe two H2A.Z binding proteins with seemingly opposing function: VPS72, an SRCAP subunit that aids in H2A.Z deposition, and ANP32E, a histone chaperone […]
• Sex differences in LDL-C genetic architecture and statin efficacy in All of Us
  February 6, 2026 by Jaclyn L Liquori
  Low-density lipoprotein cholesterol (LDL-C) is a well-established and modifiable risk factor for cardiovascular diseases (CVDs), which has been the leading cause of mortality among women and men in the United States since 1921. Despite research demonstrating sexually dimorphic symptom presentation of CVD, women remain underdiagnosed and […]
• Rheinheimera sp. T2C2 Bacterial Biofilm for Bioremediation of Cobalt (II)
  February 6, 2026 by Ellen W van Wijngaarden
  Toxic metals, including cobalt, are often the cause of contamination of rivers and lakes in mining regions. Heavy metal water pollution has been linked to numerous human health problems, prompting the need for environmental remediation. Existing techniques for removing heavy metals from water, such as chemical […]
• Cohesin-mediated chromatin organization controls the differentiation and function of dendritic cells
  February 6, 2026 by Nicholas M Adams
  The cohesin complex extrudes chromatin loops, stopping at sites bound by CCCTC-binding factor (CTCF) and organizing chromosomes into topologically associated domains, yet biological implications of this process remain obscure. We show that cohesin controls the in vivo differentiation and function of murine antigen-presenting dendritic cells (DCs), […]
• Specialization of male reproductive tactics correspond with large gonads and small brains
  January 31, 2026 by Helen Stec
  Sexual selection has strong effects on gonad size, which has been proposed to shift energetic allocations, resulting in concomitant decreases in brain size. However, mixed findings leave it unclear whether negative correlations reflect direct energetic trade-offs or selection on trait combinations broadly. We tested whether male […]