PubMed Vertebrate Genomics Feed
This is an RSS feed from PubMed (https://pubmed.ncbi.nlm.nih.gov/) of the 20 most recent papers published by CVG Members.
- by Ioannis NtekasIntermicrobial and host-microbial interactions are critical for the functioning of the gut microbiome, but few tools are available to measure these interactions in situ. Here we report a method for broad spatial sampling of microbiome-host interactions in the gut at high resolution (1 µm). This method […]
- by Severine B S W HexFrom spider dances to human language, multimodality is ubiquitous in natural communication systems. Much scholarship has been devoted to investigating why multimodality evolved and the role it plays in communication. Here, we highlight the role of multimodality in safeguarding the most fundamental prerequisite of all functioning, […]
- by Weiye ChenAntimicrobial resistance (AMR) poses a major global health threat, yet the effectiveness of national action plans (NAPs) remains uncertain. Here we developed a multidimensional One Health governance index through a structured Delphi expert consultation to evaluate AMR governance across 193 countries (2017-2022), integrating 269 policy documents, […]
- by Yishai Eisenberg[This corrects the article on p. 415 in vol. 16, PMID: 39958867.].
- by Bonnie K PatchenCONCLUSIONS: Our GWAS meta-analyses identified numerous genetic loci associated with lung function decline. These findings contribute knowledge to the genetic architecture of lung function decline, provide evidence for a role of corticosteroids in the etiology of lung function decline, and identify drug targets meriting further study […]
- by Katherine DriscollCalcific aortic valve disease (CAVD) is a degenerative disease with wide prevalence in the aging population and a low survival rate after onset of symptoms, yet there are no effective pharmacological treatments. Many patients present to the clinic with symptoms at end-stages of CAVD, when the […]
- by Elizabeth RileyINTRODUCTION: The locus coeruleus (LC) undergoes age-related changes and is involved in Alzheimer's disease pathogenesis. Vagus nerve stimulation (VNS) may modulate LC activity and could be used therapeutically, but age-related differences in VNS responses remain unexplored.
- Diverse microbial exposure exacerbates the development of allergic airway inflammation in adult miceby Jessica ElmoreExposure to a diversity of microbes has been implicated in playing a major role in susceptibility to the development of allergic lung-type diseases. The hygiene hypothesis suggests that those exposed to a broad diversity of microbes are more likely to be protected against developing allergic-type diseases. […]
- by Shirley ChuFeline oral squamous cell carcinoma (FOSCC) and human head and neck squamous cell carcinoma (HNSCC) are the 4th most common malignant neoplasms in cats and humans. Most cats are not treated due to the poor prognosis and die of their disease within a few months of […]
- by Pius N AmarteyThree-dimensional (3D) culture systems that recapitulate the tumor microenvironment are essential for studying cancer cell behavior, drug response, and cell-matrix interactions. Here, we present a detailed protocol for generating 3D spheroid cultures from murine breast cancer cells using methacrylated gelatin (GelMA)-based bioink and a CELLINK BioX […]
- by Hsin-Yun ChangHeat hormesis describes the beneficial adaptations resulting from transient exposure to mild heat stress, which enhances stress resilience and promotes healthy aging. While heat hormesis is widely observed, much remains to be learned about its molecular basis. This study bridges a critical knowledge gap through a […]
- by Cole T KwasCONCLUSION: Patients with higher preoperative disability, as determined by PROMIS PF, experience similar postoperative pain scores, narcotics consumption, time to discontinue narcotics, and return to activities as compared with patients with lower preoperative disability undergoing CDR as well as greater absolute improvements and MCID achievement rates […]
- by Jonathan T ButcherChildren with congenital heart valve disease require repeat surgical procedures to resize grafts. A new option is a valved stent that grows spontaneously.
- by Ohad PeledHabitat fragmentation is one of the most immediate and substantial threats to biodiversity, generating isolated populations with reduced genetic diversity. Genetic monitoring has become essential for detecting fragmentation and tracking its progress. However, the coherent interpretation of genetic monitoring data and understanding the genetic consequences of […]
- by Alina N StelickMaple Syrup is an important agroforestry product in New York State (U.S. Department of Agriculture (USDA), National Agricultural Statistics Service, 2017), produced from the sap of maple trees in late winter-early spring. Climate change has compressed the sap harvesting season due to increased average temperatures and […]
- by Jason A CarterCONCLUSIONS: Our findings demonstrate that immune resistance in FLC is mediated by both local T-cell exclusion and exhaustion, with combination CXCR4 and PD-1 blockade acting cooperatively to overcome these independent mechanisms. These results highlight the versatility of the human TSC system to aid in the study […]
- by Gening DongCONCLUSION: We identified hemodynamic force and tissue mechanics as drivers of local tissue development and important stimuli for OFT remodeling and septation, advancing insights in how mechanical forces contribute to OFT development.
- by Siwen XueMuscle cell fusion is critical for the formation and maintenance of multinucleated myotubes during skeletal muscle development and regeneration. However, the molecular mechanisms directing cell-cell fusion are not fully understood. Here, we identified platelet-derived growth factor receptor β (PDGFRβ) signaling as a key modulator of myocyte […]
- by Andreas StephanouStore-operated calcium entry (SOCE) plays a critical role in regulating intracellular calcium signaling and is essential for immune cell functions. SOCE blockade with the pyrazole derivative BTP2 has been explored as an anti-inflammatory strategy in preclinical models, and Zegocractin (CM4620) is under clinical investigation as a […]
- by Jie LuoDNA hydrogels are promising materials for biosensing, but translating their molecular recognition capabilities into portable diagnostics is hindered by slow target diffusion, signal constraints, and bulk architecture. Here, we present a smart DNA hydrogel-responsive sensing platform termed Q-RAPID (Quick Response Analysis for Pathogen Identification Device) for […]