This is an RSS feed from PubMed (https://pubmed.ncbi.nlm.nih.gov/) of the 20 most recent papers published by CVG Members.

• The Identification and Impact of 3'UTR Regulatory Variants on Phenotype and Disease
  August 21, 2026 by Alexis Dziubek
  Genetic variation is a major cause of disease susceptibility, and sequence variants can change both protein function and stoichiometry. Though posttranscriptional regulation is a major component of mammalian gene expression control, single-nucleotide polymorphisms (SNPs) within 3' untranslated regions (UTRs) remain an underexplored source of variation impacting […]
• Isolation and Proteomic Characterization of Outer Membrane Vesicles in Fusobacterium nucleatum
  August 19, 2026 by Jinjing Liu
  Fusobacterium nucleatum is an anaerobic Gram-negative bacterium associated with periodontal disease and colorectal cancer. Outer membrane vesicles (OMVs) produced by F. nucleatum are nanoscale lipid vesicles enriched with immunogenic and virulence-associated proteins, making them promising candidates for vaccine development. This protocol describes a comprehensive workflow for […]
• Legionella effector RavH is a tandem WH2-like domain-containing PI(3)P-dependent actin nucleator
  August 17, 2026 by Qing Zhang
  Legionella pneumophila infects and replicates within protozoa and macrophages in a specialized compartment termed the Legionella-containing vacuole. To establish this niche, the bacterium delivers more than 350 effector proteins through its type IV secretion system to modulate host pathways and prevent phagolysosome fusion. Here, we identify […]
• Neuroepithelial reprogramming and ERBB vulnerability in canine acanthomatous ameloblastoma
  August 15, 2026 by Andreas Stephanou
  Canine acanthomatous ameloblastoma (CAA) is a locally invasive benign oral neoplasm that is difficult to distinguish from canine oral squamous cell carcinoma (COSCC) due to overlapping features. Previous studies using bulk RNA sequencing (RNA-seq) have demonstrated pronounced differences in programs related to hypoxia and cell proliferation. […]
• Excess folate elevates formaldehyde genotoxicity in cell lines but not in mice or humans
  August 12, 2026 by Christopher Mellor
  Folate metabolites are chemically unstable: spontaneous decomposition releases formaldehyde, a genotoxin in blood stem cells and a human carcinogen. Despite this, folic acid consumption frequently exceeds the Recommended Dietary Allowance and is prescribed at high doses for patients with blood disorders. However, the impact of excess […]
• Vasotocin influences mother-offspring associations in a facultatively family-living lizard
  August 8, 2026 by Jai Lake
  Parent-offspring associations provide the basis for more complex care and breeding systems. One proximate mechanism by which parental behavior is facilitated across animal taxa is via nonapeptide hormones such as arginine vasotocin (AVT). However, existing research largely comes from obligately social species, and whether such mechanisms […]
• Role of pks + Escherichia coli in colorectal cancer: Mechanisms, clinical evidence, and therapeutic perspective
  August 7, 2026 by Sina Nasrollahian
  Colorectal cancer (CRC) is a multifactorial disease influenced by genetic, environmental, and microbial factors. Among gut microbiota, pks^(+)Escherichia coli has emerged as a key contributor to colorectal carcinogenesis through the production of colibactin, a genotoxic secondary metabolite. Colibactin induces DNA damage by forming interstrand crosslinks and […]
• Regression-Associated Macrophages Recruit Natural Killer Cells that Constrain Targeted Therapy Resistance
  August 5, 2026 by Chia-Hsin Hsu
  Targeted kinase inhibitors induce marked tumor regressions but are limited by the emergence of drug-tolerant residual disease and resistance. Although tumor-intrinsic and adaptive immune mechanisms have been extensively studied, a better understanding of the contribution of innate immunity to targeted therapy durability is needed to devise […]
• Intraoral Radiographic Description of Dental Anatomy and Pathology in the Virginia Opossum (Didelphis virginiana)
  August 3, 2026 by Cailin E Winokur
  While the gross dental anatomy of the Virginia opossum (Didelphis virginiana) has been described, the radiographic appearance of the dentition and the prevalence of dental and oral pathology have not been comprehensively evaluated. The objective of this study was to characterize the intraoral radiographic dental anatomy […]
• Accurate de novo transcription unit annotation from run-on and sequencing data
  August 3, 2026 by Paul R Munn
  Functional element annotations are critical tools used to provide insight into the molecular processes governing cell development, differentiation, and disease. Run-on and sequencing assays measure the production of nascent RNAs and can provide an effective data source for discovering functional elements. However, the accurate inference of […]
• Ultrasonographic assessment of in utero fetal presentation, position and posture can be essential: case report
  August 3, 2026 by Catherine Renaudin
  The objectives of this clinical case report were to highlight the value of late transrectal ultrasound examination for assessing fetal presentation, position and posture and to describe the management of a case of malposture associated with musculoskeletal and cerebellar abnormalities, including its in utero ultrasound diagnosis […]
• Advances in RNA pesticides and nano-delivery systems
  August 3, 2026 by Huihui Liu
  RNA pesticides have garnered considerable attention in pest management due to their exceptional selectivity, environmental safety, and flexible design. They interfere with essential physiological processes in pests by silencing key genes, thereby achieving effective pest control. Moreover, RNA pesticides can target genes related to detoxification enzymes […]
• Polioencephalomyelitis and neuronal necrosis caused by canine parvovirus-2a variant in free-ranging juvenile mountain lions (Puma concolor)
  July 31, 2026 by Omar A Gonzales-Viera
  Canine parvovirus 2a (CPV-2a) causes severe enteritis and diarrhea in unvaccinated domestic puppies and wild mesocarnivores, such as raccoons (Procyon lotor). A retrospective and prospective study was conducted to characterize CPV-induced encephalomyelitis in mountain lions (Puma concolor) from California. Four free-ranging juvenile mountain lions were euthanized […]
• Molecular architecture of excitatory and inhibitory neurons in the first gustatory relay
  July 29, 2026 by Deepthi Mahishi
  Taste perception is a major determinant of food intake and is dynamically modulated by hunger and satiety signals across species. While the peripheral and cortical representations of taste sensory stimuli are well characterized, far less is known about how metabolic state shapes taste processing in subcortical […]
• piRNA loss unleashes episodic transposition bursts
  July 29, 2026 by Peiwei Chen
  In Metazoa, transposon expression is suppressed by the piRNA pathway, and disruption of this pathway leads to rampant transposon expression. However, it remains unclear whether increased transposon expression results in actual transposition, and if so, which and how frequently transposons mobilize upon piRNA loss. Here, we […]
• Aldehyde Detoxification in Cancer: Metabolic Guardians of the Genome
  July 28, 2026 by Brandon T James
  Reactive aldehydes are potent electrophiles that damage DNA and can ultimately promote cancer. While many aldehydes are ubiquitous in the environment, mammalian metabolism also generates high levels of endogenous aldehydes sufficient to threaten genome integrity. To protect against these aldehyde genotoxins, mammalian cells rely on diverse […]
• Presence of a home cage running wheel, but not wheel running per se, decreases social motivation in adult C57BL/6J female mice
  July 28, 2026 by Patryk Ziobro
  Physical activity offers myriad benefits to health and well-being, in humans and other animals as well. In rodents, voluntary wheel running can attenuate the effects of both physical and social stressors on rodent social behavior. Whether wheel running affects rodent social behaviors per se remains less […]
• Is Chunking Ability Unitary Across Levels of Linguistic Representation?
  July 26, 2026 by Cristian Rivera
  Much like with statistical learning, there is a tendency in the cognitive and language science literature to treat chunking as a unitary, domain-general ability that operates fairly similarly across domains of cognition. An alternative position suggests chunking in language and cognition involves multiple mechanisms tuned to […]
• Resistant starch types 2 and 4 induce distinct and reversible changes in the human gut microbiome
  July 24, 2026 by Elisa Piperni
  Resistant starch (RS) can confer benefits for the gut microbiome and host cardiometabolic health. However, different types of resistant starch can differentially affect gut microbiome composition and functional capacity, especially given interindividual variability in responses, thus limiting the application of resistant starch in dietary strategies. We […]
• Analysis of ADVIA Myeloperoxidase Cytogram LUC Angle Does Not Distinguish Acute Myeloid Leukemia From Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma in Dogs
  July 23, 2026 by Mayzie Miller
  CONCLUSIONS: The angle of the LUC population on the ADVIA MPX cytogram cannot be used as a rapid test to differentiate AML from LL.